OSferion-Bone void filler-

Device Description

OSferion is a white porous material composed of high purity beta-tricalcium phosphate.
It is intended to fill bony defects that are not intrinsic to the stability of the material and has properties that allow it to be replaced by autologous bone after implantation.
OSferion can reduce the amount of autologous bone harvesting or even avoid autografting depending on the case.

Features


SEM image

  • High purity beta-tricalcium phosphate (β-TCP)
  • Good biocompatibility
  • Sufficient absorbable properties
  • Replaced by autogenous bones
  • 75% porosity
  • Macro pores and micro pores
  • Optimum pore diameters for good bone in-growth
  • Interconnection pores structure allows for good cell infiltration

Specifications

Molecular formula
Ca3(PO4)2
Molecular weight
310.18
Generic name
β-tricalcium phosphate
Properties
Porous material
Porosity
Approx. 75%
Pore Size
100 - 400 μm
Form
Block, Cylinder, Granule

Availability

BlockCylinderGranule
Japan
China

= Available

= Currently Not Available

Launch

Japan since 1999
China since 2008

Indications

OSferion is indicated to be gently packed or placed into bony voids or gaps of the skeletal system (i.e. the extremities spinc and pelvis.) that are not intrinsic to the stability of the bony structure. Following placement in the bony void or gap, the calcium phosphate scaffold resorbs and is replaced with bone during the healing process.

Bone replacement

Evaluation of bone replacement in rabbits

*V.Goldner Stain


3W


6W


12W

*X-ray pictures


4W


8W


12W

SEM images

The SEM images below shows that OSferion works as a good scaffold for osteocytes